Manchester United's injury crisis has worsened with the news defender Nemanja Vidic will miss their Champions League tie at Wolfsburg on Tuesday.
The Serb has a flu bug and been left at home, with United already through to the last 16 of the tournament.
Vidic joins Rio Ferdinand, Wes Brown, Gary Neville, Rafael da Silva, Fabio da Silva, Johnny Evans and John O'Shea on the sidelines for United.
Michael Carrick will play at centre-back, possibly with Darren Fletcher.
Fletcher was expected to fill in at right-back but could now be forced to move to the centre following Vidic's withdrawal from the squad, although Patrice Evra could be another option.
United had hoped Vidic would have recovered from the flu bug that kept him out of Saturday's win at West Ham, but he failed to make the flight to Germany.
Oliver Gill, son of chief executive David, Magnus Eikrem, Cameron Stewart, Matt James and Oliver Norwood are all unfamiliar faces who were included in United's 19-man squad.
United have already booked their place in the Champions League knockout stages but still need a point to be sure of finishing top of the group, which would theoretically give them an easier tie in the next round.
Midfielder Paul Scholes said: "We want to win the game and finish top of the group.
"How much difference that makes to who we get in the next round, I am not too sure. There are lots of good teams at that stage of the tournament."
Central mid field pair to central defensive pair!!!