Liverpool v Everton
In recent years there has not been much more than local pride at stake when Liverpool and Everton have locked horns in the Merseyside derby...
But times they are a changing.
The Blues' renaissance under David Moyes is well and truly under way and they are no strangers to finishing above the Reds - they secured fourth place in Rafa's first season at Anfield in the 2004/05 season.
This year there is a similar situation developing at the top, as we battle it out with Everton for the fourth and final Champions League spot.
Many believe the result of the 207th Merseyside derby will go some way to determining who takes their place amongst Europe's elite, although that wasn't the case back in 2005 when the Reds won 2-1 at Anfield but ended up finishing fifth.
Liverpool have already beaten the Blues this season after Dirk Kuyt's double from the penalty-spot clinched a 2-1 success and they will be aiming to send Moyes and his men home empty-handed on this occasion, to secure not only the double over their nearest rivals, but also a psychological edge in the race for fourth.