Chelsea v Liverpool
Liverpool head to Stamford Bridge knowing that a victory would not only bring an end to Chelsea's amazing unbeaten home record but it would also see them move clear at the top of the table.
Both sides are the only remaining teams yet to be beaten in England's topflight and even without their respective leading goalscorers in Didier Drogba and Fernando Torres, it promises to be the biggest game of the season to-date.
The Reds picked up a point at the Bridge last season but were knocked out of both the Carling Cup and the Champions League on the Blues' home turf.
Rafael Benitez will feel his side are due a turn of luck against Luiz Felipe Scolari's team and Sunday's clash would be the perfect time for it to happen.