I think there is a difference regarding 1-2 or 2-1.
Because, at 1-2, I want that our two forwards to stay more upfront and defend close to the midfield line. Let the trequartista run more, especially when we seek a goal.
In the last games, I really hated to see Pandev and Zarate and even Rocchi defending so deep towards midfield. That is why we find it difficult to start attacking cause there is just too much field to run to the goal.